ROLE OF FUNCTIONALIZED GUAR GUM IN SOLID DISPERSION OF NON-STEOIDAL ANTI-INFLAMMATORY DRUG

The current investigation was developed to study the role of functionalized guar gum as carrier in solid dispersion iboprofen. technique using aminated would be an effective approach for increasing solubility and dissolution behaviour ill fathomable medicament than native gum. results FTIR DSC studies confirmed that there is no chemical interaction or incompatability between drug excipients. invitro performed prepared formulations. Based on SD3 shown highest release 99.41% within 24hrs. Stabiliy conducted per ICH guidelines falloutsrevealed physical change.it may concluded ibuprofen can br improved by dispersion, which provides a wide scope therapeutic efficiency.